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Misconduct and the Body of Knowledge

At her blog, Janet Stemwedel discusses how difficult it is to remove dishonest works from the scientific literature. "You would hope that one consequence of identifying scientists who have made dishonest contributions to the scientific literature would be that those dishonest contributions would be removed from that literature," she says. Stemwedel then points to an article in Science and Engineering Ethics from Anne Neale and her colleagues that looked into that question. The researchers identified suspect articles and then looked to see whether they had been retracted. Of 102 articles, nearly half had a retraction, a quarter an erratum, others included a comment or a link to NIH's 'Findings of Scientific Misconduct,' and four didn't show up in PubMed. Three, however, were unlabeled. Then by searching Web of Science, the researchers found 6,000 citations to those 102 papers. "Some of the problem … may be due to the vigilance (or lack thereof) displayed by those using the scientific literature, but some of it may come down to the extent to which that scientific literature is accessible to the researchers," Stemwedel notes.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.