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Microfluidics-based PSA Diagnostic Device Produces Rapid Results

In MIT's Technology Review, reporter Emily Singer examines new microfluidics technology from the Woburn, Mass.-based Claros Diagnostics, which can detect prostate specific antigen levels in only 15 minutes. "If approved by the US Food and Drug Administration, the device will be one of the first examples of long-awaited microfluidics-based diagnostics tests that can be performed in the hospital or doctor's office," according to Tech Review. The disposable microfluidics cartridge, about the size of a credit card, requires only a small drop of blood; the reader, comparable in size to a toaster, "could, in theory at least, be adapted to detect any number of different proteins," Singer writes. The company is currently running clinical trials — which compare the utility of its device to standard prostate specific antigen testing — and expects results within a few months. Claros hopes to launch their device in Europe later this year and in the US in 2011.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.