Of Mice and Women

Nature News reports that the lack of female research participants — from basic research in animals to clinical trials with human patients — has significant consequences, such as, "for example, when drug candidates fail to get regulatory approval because they don’t work in women in late-stage clinical trials." Nature notes that researchers tend to prefer the use of male lab animals to limit the potential for the variability of female animals’ estrous cycles, and that the ratio of male- to

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