Of Mice and MicroRNA

A new paper out of Harvard screened embryonic stem cells and found a factor called Lin-28 that inhibits Drosha, which usually cleaves the ends of miRNAs. Lin-28, though, only prevents the processing of miRNAs belonging to the let7 family. The authors suggest that Lin-28 then may prevent miRNA-mediated differentiation in stem cells and some cancers.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.