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Of Mice and MicroRNA

A new paper out of Harvard screened embryonic stem cells and found a factor called Lin-28 that inhibits Drosha, which usually cleaves the ends of miRNAs. Lin-28, though, only prevents the processing of miRNAs belonging to the let7 family. The authors suggest that Lin-28 then may prevent miRNA-mediated differentiation in stem cells and some cancers.

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A South African university has told the Wellcome Sanger Institute to return DNA samples it has from indigenous African communities, The Times reports.

The University of California, Berkeley's Rasmus Nielsen and Xinzhu Wei have retracted their CCR5 gene paper due to a technical artifact.

 

University of Virginia researchers are exploring a genetic risk test to gauge type 1 diabetes risk, NPR reports.

In PNAS this week: researchers compare two high-grade neuroendocrine lung cancers, height among ancient Europeans, and more.