Eric Lander's group has a new paper in the advance online section of Nature in which they describe how they used high-throughput reduced representation bisulphite sequencing coupled with single-molecule-based sequencing to generate DNA methylation maps from mouse primary tissues, including embryonic stem cells, embryonic-stem-cell-derived, and primary neural cells.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.