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Measuring miRNA Isn't So Hard Anymore...

Researchers at the Mitchell Cancer Institute compared expression stabilities of miRNA from fresh frozen and formalin-fixed, paraffin-embedded samples, providing first-time evidence that FFPE samples might be used to study miRNA expression in cancer and other diseases. Using high-throughput, locked nucleic acid-based miRNA arrays and miRNA qRT-PCR analysis, they found that the two showed good correlation and that among 40 colorectal cancer FFPE samples, there was no significant difference of miRNA expression. Their published research can be found in RNA.

 

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.