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Cheap Sequencing to the Clinic

Speaking with a reporter from the Edinburgh Evening News, Mark Blaxter says that whole-genome sequencing is "going to be part of standard clinical practice very soon." Blaxter, a professor at the University of Edinburgh, adds that while clinical sequencing shows much promise, its practice incurs complex ethical quandaries. Blaxter also outlines advances in sequencing technology, and how scientists have applied them along the way.

"I sequenced 3,000 letters of a genome of a small parasite that causes a nasty disease in India for my PhD. Cutting edge at the time, it took three years to do," he tells the Evening News. "The machines we use today can sequence 300 billion bases in 10 days. It's now cheap, accessible and there are all sorts of possibilities with this technology."

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.