Scientists at Orion Genomics and other labs, including Cold Spring Harbor, have used microarrays in a genome-wide screen to look for epigenetic biomarkers for early stage detection of breast cancer. In the study, published yesterday in PLoS ONE, they found about 200 loci that were differentially methylated, and then went on to validate these in 230 clinical samples.

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

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