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May the Best App Win

Coming up at the end of this week is the deadline for the Binary Battle. Mendeley and PLoS got together to hold this contest to encourage the development of apps that science more open using Mendely or PLoS Application Programming Interfaces. And why participate? "The most important reason to build a science app, even if not with Mendeley or PLoS's APIs, is to do something awesome for the world instead of just the next music app," writes Jason Hoyt at Mendeley's blog. "Boosting the number of tools available to researchers using accessible data is the entire raison d'être." In addition, Mendeley's webpage says there is $16,000 in award money to be had. The deadline is September 30.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.