Skip to main content
Premium Trial:

Request an Annual Quote

Mass Spec Mania

This week's issue of PNAS focuses on mass spectrometry and "attempts to illustrate the breadth and uniqueness of applications of molecular MS to a variety of scientific fields with current examples." Matthias Mann and Neil Kelleher write about how the latest generation of mass spectrometers has helped proteomics come of age and how precision proteomics is now possible. One paper reports on using DESI-MS imaging to see the distribution of clozapine, an antipsychotic drug, and its metabolite in brain, lung, kidney, and testis samples. In another, Vanderbilt researchers used imaging MS to look at Aβ isoform distributions in Alzheimer's plaque samples, mouse brain protein maps, and protein distribution in breast carcinoma. Other papers cover petroleomics, detecting extraterrestrial aromatic molecules, nanocalorimetry, among other topics.

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.