Researchers led by Lee Hood have found proteins that seem to signal the onslaught of mad cow disease, reports Technology Review. The scientists took a global approach: they infected mice with prions and followed the resulting gene expression changes in the mice brains, resulting in 30 million data points. They narrowed the implicated genes down to 300, noting that the proteins can be seen in the mouse bloodstream about eight to 10 weeks before the onset of symptoms. Tech Review adds that Hood and his colleagues hope to commercialize a test for the human and bovine forms of the disease based on these biomarkers.
Marking Mad Cow
Mar 25, 2009