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Mapping Methylation Across Cancers

Mar 26, 2008

A study published in PNAS yesterday details a "unique" method for mapping DNA methylation changes across different cancer types. Researchers at the Ludwig Institute for Cancer Research measured quantitative methylation patterns in a set of about 400 candidate genes across 59 cancer cell lines and found that 78 of them are epigenetically changed, 35 are changed in only one tumor type, and seven are changed in more than one type of cancer.

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