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Mapping Methylation Across Cancers

A study published in PNAS yesterday details a "unique" method for mapping DNA methylation changes across different cancer types. Researchers at the Ludwig Institute for Cancer Research measured quantitative methylation patterns in a set of about 400 candidate genes across 59 cancer cell lines and found that 78 of them are epigenetically changed, 35 are changed in only one tumor type, and seven are changed in more than one type of cancer.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.