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Making In Vitro Translation Work

Bitesize Bio covers tips for cell-free protein synthesis, or in vitro translation. One, you get better protein yields; two, it's an optimal environment for protein production; and three, there's no concerns about cell viability. Nick also discusses the best expression systems for prokaryotic and eukaryotic cells. "The choice of the system should be determined not just by origin but also by the biological nature of the protein and the requirements of downstream applications," he writes.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.