Skip to main content
Premium Trial:

Request an Annual Quote

Making Sense of it All

An estimate in Nature says that about 30,000 human genomes will be sequenced this year, "but what's missing, say a growing chorus of researchers, is a way to make sense of what these endless strings of As, Gs, Cs, and Ts mean to individuals and their health," writes David Ewing Duncan at MIT's Technology Review. However, he adds that people in the field are working to rectify that problem. For example, Duncan reports that Complete Genomics' Clifford Reid has called for companies to develop standard processes for collection though analysis of DNA samples while Pacific Bioscience CSO Eric Schadt and Stephen Friend, who used to be at Merck, founded Sage Bionetworks to standardize DNA databases. "This won't happen overnight," Schadt tells Duncan. "But it will be huge, like the Internet."

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.