Studying gene function using RNAi can be difficult unless you can identify your novel hits from your off-target effects. On his blog, Keith Robison suggests pooling siRNAs so their on-target effects are additive and the off-target ones are reduced. To minimize siRNAs from affecting one another, he also suggests having the siRNAs compete for a limited target.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.