Make Your siRNAs Compete | GenomeWeb

Studying gene function using RNAi can be difficult unless you can identify your novel hits from your off-target effects. On his blog, Keith Robison suggests pooling siRNAs so their on-target effects are additive and the off-target ones are reduced. To minimize siRNAs from affecting one another, he also suggests having the siRNAs compete for a limited target.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.