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For the Love of Kumquats

Keith Robison, lead senior scientist at Infinity Pharmaceuticals and Omics! Omics! blogger, loves citrus. In a recent post, he discusses his anticipation for the completion of the citrus genome project at the Department of Energy’s Joint Genome Institute. “What I’d really like is to have the genetic blueprint for all those wonderful flavors…” Robison writes. “Imagine if you could have a whole series of clementine-like fruits, with the size and easy peeling characteristics but with the whole range of other citrus flavors and colors genetically grafted in ― cara cara clementines and blood clementines and ruby red clementines and perhaps even sweet lemontines and key clemenlimes,” he muses.

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.