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A Look at GATK

Dan Koboldt at MassGenomics says next-gen sequencing has presented some problems for the bioinformatics community in terms of the sheer amount of data being generated. Tools for sequencing data analysis are under demand for efficiency, flexibility, and scalability, he says. A key development in this field was the Sequence Alignment Map, but now, researchers at the Broad Institute have come out with the latest advance — the Genome Analysis Toolkit.

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