In the Pipeline's Derek Lowe takes a look at chemical biology, and says that the combination of organic chemistry and molecular biology is "one of the most interesting and productive research frontiers." While biologists have been looking at genes and their proteins, mutating and manipulating them in living systems, chemists have been working with enzymes as a way of controlling molecules.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

The Wall Street Journal looks into the cost of new gene therapies.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.