Steinn Sigurðsson at the Dynamics of Cats posts a PDF (it's long, but a good read) of Rick Trebino's 123 steps, plus an addendum, to publishing a comment in a scientific journal. The first step is to "read a paper in the most prestigious journal in your field that 'proves' that your entire life's work is wrong," then to realize there are lots of errors in that paper, follow it up by deciding to write and prepare a comment. It's all downhill from there. Step 84 is:
A Long and Ultimately Fruitless Road
Aug 17, 2009
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