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Lined Up To Be Sequenced

A Reuters story looks into sequencing and health research, particularly focusing on the UK Biobank, a project that aims to enroll 500,000 people to have their DNA sequenced and their health tracked over time. The biobank investigators hope to find rare variants linked to common diseases, building on the work of others, including Decode. Another area of particular interest for sequencing technologies, the article continues, is cancer. "Cancer is maybe the best disease to cut our teeth on," Yale's Richard Lifton tells Reuters. "The reason for that is we know that cancer is largely a disease in changes of DNA sequence." This sidebar to the article also gives a run-down of the big sequencing and analysis players.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.