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Line Them Up

At Genomes Unzipped, Luke Jostins gives his thoughts on Oxford Nanopore's GridION platform, which is the basis for all of the company's DNA, protein, and small molecule analysis applications. Jostins says that the machines appear to be bench top-friendly, but also scalable. "The boxes are designed to fit together in standard computing cluster racks, and … connect together via a standard network," he says. Jostins also makes an estimate of what the throughput of a machine might be. With some assumptions, he calculates that "a single machine would be running about 500 Mbp/hour; this is a 30X genome in a week." Jostins adds that "nanopore technology is making solid advances towards working machines, and that these machines could be game-changers."

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.