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"Light" Smoking is No Refuge from Lung Cancer

The University of Cincinnati's Marshall Anderson and his colleagues in Genetic Epidemiology of Lung Cancer Consortium uncovered a risk locus on chromosome 6q that increases a person's risk of developing lung cancer even if that person is a light smoker. The study, which is published in Cancer Research, found that for family members born without this variant, the risk of developing lung cancer tracked very closely with level of smoking — smoke more, have a higher risk of lung cancer. But in family members born with this risk haplotype, even light smoking resulted in greatly increased risk for developing lung cancer, and increasing smoking only marginally increased the risk.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.