Over at Omics! Omics!, Keith Robison ponders the use of the term "exome sequencing," which he worries is being "taken a bit too literally." "It is true that these approaches catch a bit of surrounding DNA due to library construction and the targeting approaches cover splice junctions, but what about some of the other important sequences?," he writes. "There are quite a few well annotated non-coding regions of functional significance. An obvious case are promoters." Robison says that as costs drop, he images the community will migrate to full genome sequencing anyway.
Let Us Interest You in a Genome Sequence Instead
Oct 15, 2009