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Let Us Interest You in a Genome Sequence Instead

Oct 15, 2009

Over at Omics! Omics!, Keith Robison ponders the use of the term "exome sequencing," which he worries is being "taken a bit too literally." "It is true that these approaches catch a bit of surrounding DNA due to library construction and the targeting approaches cover splice junctions, but what about some of the other important sequences?," he writes. "There are quite a few well annotated non-coding regions of functional significance. An obvious case are promoters." Robison says that as costs drop, he images the community will migrate to full genome sequencing anyway.

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