Leroy Hood has co-penned an article in this month's issue of Scientific American, along with James Heath and Mark Davis, and it delves into using a systems approach to model complex diseases like cancer. Extensive work goes into creating computational models that can predict disease progression in say, prostate cancer, but knowing the molecular pathways involved can help with early detection and stratification. The article also covers nanoscale therapies, like RNAi, and looks ahead. "Once the principles of nanoparticle function in humans are more fully established, the concept can be applied to create a therapeutic system that can carry combinations of drugs, each with its own customized release rates," they write.
Lee Hood on Nanomedicine
Jan 21, 2009