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Leave That GWAS Alone

The New York Times profiles Duke's David Goldstein, calling him a dissenting voice above the common disease/common variant hypothesis. Goldstein says that common diseases are probably caused by many rare variants and that doing more and more genome-wide association studies will largely be fruitless. "It's an astounding thing that we have cracked open the human genome and can look at the entire complement of common genetic variants, and what do we find? Almost nothing. That is absolutely beyond belief," he says. Goldstein also has a new book, called Jacob's Legacy, that recounts his studies into Jewish genetic history.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.