Laying Out the Map

The Ohio State University has a white paper on personalized medicine that discusses the university's model for employing personalized medicine at its medical center. OSU will be taking a four-stage approach -- from discovery, particularly using a systems-based approach, to developing preclinical trials and experimental therapeutics to then implementing those new strategies, and finally to disease prevention strategies.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.