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Lack of Affinity

Over at Omics! Omics!, blogger Keith Robison offers his two cents on a European consortium set to generate a slew of affinity reagents aimed at the human proteome. He writes:

They will need a lot of luck (and copious quantities of money), but the lack of off-the-shelf affinity reagents for any protein of sudden interest is a serious handicap for validating array or computational experiments, as I found all too often in my last job.

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.