Keeps on Coming

Roche is letting 6 percent of its workforce, or about 4,800 people, go, reports Ed Silverman at Pharmalot. A Roche statement on its Operational Excellence Program says that 800 cuts will be to product development staff and 600 cuts to research and early development positions, while sales and marketing will bear the largest share of the cuts, with a loss of 2,650 positions.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.