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Keeping Up Databases

An editorial appearing in Nature last month discusses the major problem facing biological databases and repositories: funding. After providing 10 years of support, the US National Science Foundation is discontinuing its funding of the Arabidopsis Information Resource and Japan has cut the RIKEN BioResource Centre's funds by a third. The editorial says it's time for "a whole new approach." Business|bytes|genes|molecules's Deepak Singh adds that while the current model isn't working, "sustaining a data resource of any kind requires a dedicated team, a team of software engineers, curators, informaticians and biologists and funding that understands that these need to be maintained."

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.