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A synthetic base pair is replicated similarly to how natural base pairs are, report the Universität Konstanz's Karin Betz and her colleagues in Nature Chemical Biology. The researchers obtained and analyzed X-ray crystal structures of Taq DNA polymerase I bound to templates with either a natural base pair or the unnatural base pair dNaM-d5SICS at different stages of replication. From this, they found that dNaM-d5SICS is efficiently replicated.

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New US Department of Commerce rules will affect supercomputing in China, according to the Wall Street Journal.

A new analysis finds that it will be more than a century until female computer scientists publish at the same rate as their male counterparts, ScienceInsider reports.

Broad Institute researchers describe an approach they've dubbed "DNA microscopy."

In PLOS this week: epigenetic changes following hepatitis C virus treatment, metagenomic analysis of Ugandan children with febrile illness, and more.