Research reported in this week's JAMA looked at the global DNA methylation pattern of 111 Icelandic people and 126 Utahan people at different points in time. The researchers saw that the DNA methylation patterns changed over time -- in both groups, about 10 percent of individuals had more than 20 percent methylation change over time.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.