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Up Just One Creek

A rare Colorado trout may be even more elusive than previously thought, reports The New York Times' Green blog. The greenback cutthroat trout, which is the state fish of Colorado, was thought to live in five wild populations, but a recent study of current fish populations, preserved samples, and historical stocking records indicates that there is only one wild population of the trout, the Times says. The study, published in Molecular Ecology, examined DNA samples from museum greenback cutthroat trout specimens and performed a phylogenetic analysis of the historical samples, which they then compared to modern lineages. The researchers say that the surviving population, which is outside the fish's historical range, is likely descended from fish stocked by a hotel owner to encourage visitors, the Times adds. The other populations are of trout from "phylogenetically and geographically distinct sources," the researchers write.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.