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That "Junk" Sure is Interesting!

At Genomicron, blogger T. Ryan Gregory links to a paper out of UCSC that delves into one form of noncoding DNA, endogenous retroviruses. He notes that "roughly 8% of the human genome is represented by ERVs, which are descendants of former exogenous retroviruses that became incorporated into the germline genome." The PNAS paper, published by David Haussler’s lab, found that more than one-third of p53 binding sites are accounted for by ERV copies with a p53 site, seriously shaping p53's transcriptional network.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.