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That "Junk" Sure is Interesting!

At Genomicron, blogger T. Ryan Gregory links to a paper out of UCSC that delves into one form of noncoding DNA, endogenous retroviruses. He notes that "roughly 8% of the human genome is represented by ERVs, which are descendants of former exogenous retroviruses that became incorporated into the germline genome." The PNAS paper, published by David Haussler’s lab, found that more than one-third of p53 binding sites are accounted for by ERV copies with a p53 site, seriously shaping p53's transcriptional network.

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.