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It's the Network, Stupid

An article in Forbes wonders, does the post-genome drug discovery process need to evolve? One scientist-radical, Peter Sorger of Merrimack Pharmaceuticals, believes it does, and he is working toward a new approach that would discover and test drugs for humans.

The article parades out a series of scientists bemoaning the lack of decent information about the basic network that runs a human being -- and how that complex system must be figured out before really intelligent drug design can be made possible.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.