University of Chicago researchers performed gene expression analysis on lymphoblastoid cell lines from 60 families, half from Utah and half from the Nigerian Yoruba population. Among 9,000 genes, they report in this American Journal of Human Genetics paper that they found almost 400 genes where expression varied -- mostly in immune response genes, says this article from the BBC. Coupled with previous work, they believe that population differences can play a large role, not only in susceptibility to disease, but also in individual response to medications.
It Turns Out We're Not All the Same
Mar 01, 2008