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According to a recent study out of Johns Hopkins, clinical trials that pay participants attract mostly poor volunteers who join repeatedly, and may enroll in multiple trials at the same time. While there is no substitute yet for human trials, the long-term health effects of repeatedly volunteering remain murky, and it could also be risky for scientific clinical validation.

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The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.