Skip to main content
Premium Trial:

Request an Annual Quote

Is it Bigger than a Breadbox?

Dan Koboldt at MassGenomics gives his take on the new Ion Torrent semiconductor sequencing instrument unveiled at the Advances in Genome Biology Technology conference in Marco Island, Fla., last week. Koboldt, who was able to view the new machine at the Ion Torrent suite, describes it as slightly larger than a breadbox. “The real engineering marvel is the semiconductor chip itself,” he writes, explaining the throughput achievable with the tiny chip that contains 1.5 million wells. In referring to the Ion Torrent CEO’s talk at the conference, the blogger writes “I can’t believe [Jonathon] Rothberg didn’t mention this ― an iPod Touch ships with each instrument, pre-installed with an app to monitor runs and cycles in real time. How cool is that?”

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.