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Introducing Systems Oenology

French researchers were able to uncover the "metabologeographic signature" of 10-year old wines from mass spec data, reports Wired Science. The wines were identical, except that they were aged in oak barrels made from trees from nine different forests. In PNAS, the researchers write, "Our systems oenology approach provides an unprecedented example of metabologeography translated into chemical representations of the way such noble nectar can shape on the papillas of the wine taster some of the outlines of the scene of its birth."

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.