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The Interaction Itinerary

In a paper published this week in PLoS Biology, senior author Tim Gardner and his colleagues attempt to validate the performance of machine learning algorithms on the genome scale using E. coli. The team mapped more than 1,000 interactions in the E. coli transcriptional regulatory network using microarrays. They've made the ensuing expression data available here, and anyone interested in checking out the CLR algorithm they used can download it here.

 

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.