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Intein Cleavage Glimpsed With Physics

The February issue of Biophysical Journal features a paper by Philip Shemella and team who describe a "quantum biology" approach to analyze the moves of inteins. With the help of computing power from Rensselaer Polytechnic Institute and University of Illinois at Urbana-Champaign, the authors zoomed in at the quantum mechanical level to check out how such a protein cuts itself out of single-celled host proteins and reconnects its strands. The hope is that this finding may lead to even more fine-tuned methods to control the mechanism, thereby paving the way for the development of intein-based nanotechnology.

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.