There are two reasons why an experiment may not be working, Dr. Isis tells one of her readers who wrote in. First, she says is that you're just not doing it right and for that, she suggests reaching out to someone who has done something similar. "You've simply got to find the person who can help you do what you need," she says. The second reason is that your methods are fine — you just aren't getting the expected results.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.