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'To Infinity and Beyond'

NASA’s National Space Biomedical Research Institute this week named three young investigators who are the recipients of two-year fellowship awards. These awards provide them with the “opportunity to manage their own space-related biomedical research project while continuing to learn from a faculty mentor,” NSBRI says. The John Hopkins School of Medicine’s Catherine Davis, Boise State University’s Liliana Mellor, and Vanderbilt University Medical Center’s Guillaume Vignaux will receive a $50,000 stipends per year to study “the health risks related to long-duration spaceflight,” among other things, the institute adds.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.