From the Economist, here's an article about how genomic variation affects people's immunity to infectious disease. In particular, the article follows scientists who believe they have found an example of "a disease that was thought to be purely infectious but which has turned out to be purely monogenic—that is, under the control of a single gene." Single genes appear to have such control in a number of diseases, including leprosy and herpes simplex, according to the article.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.