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If GWAS Made You Wary, Be Careful with Social Networking

In much the way scientists learned they could use minimal genotype data to identify "anonymized" individuals from pooled DNA samples, researchers have now determined that it is possible to ID anonymous users of social networking sites, according to this Technology Review article.

"The researchers wanted to see if they could extract sensitive information about individuals using just the connections between users, even if almost all of the names, addresses, and other forms of personally identifying information had been removed," the article says. "They found that they could, provided they could compare these patterns with those from another social-network graph where some user information was accessible."

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.