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Ideas, Please

Sally Rockey, deputy director of the extramural research office at NIH, is asking researchers for their ideas on how to manage NIH's budget in such lean times. "The biomedical research enterprise is a partnership between NIH and the extramural community, and we don't expect to make any changes to our processes without an in-depth discussion with you," she writes at the Rock Talk blog. Her office put together a report that includes various ways of managing the budget, such as limiting award sizes, capping the number of awards a PI may hold, or letting success rates fall, among others. In an interactive slide, this graph shows that limiting the number of RPG awards to three would free up $111 million for competing awards, while a four-award cap would give $28 million. Rockey adds that feedback on managing the budget may be left in the comments on her blog, or sent to [email protected]

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.