HSF2 Aids Fertility in Mice

Aug 06, 2008

A study out of the Turku Centre for Biotechnology in Finland used ChIP-chip analysis to discover that heat shock factor 2 (HSF2), a transcription factor involved in spermatogenesis, binds the male-specific region of the mouse Y chromosome long arm (MSYq) in mouse testis. Deletions in this gene are known to result in sperm head defects and impaired fertility.

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