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How Eric Green 'Got on the Human Genome Elevator'

A St. Louis Beacon profile of Eric Green examines how the National Human Genome Research Institute director — and Missouri native — began his genomics research career in his hometown. "I come from a power-science family, which is embarrassing in some ways and is a source of incredible pride in other ways," Green tells the Beacon. His father, Maurice Green — a "prominent Saint Louis University virologist," the article notes — says that both of his sons used to visit his virology lab at the SLU School of Medicine on weekends, and that Green "would discuss surgery procedures and help with experiments," when he was a young child. Green, now 50, received both his MD and PhD at WashU before entering the fledgling field of genomics while a postdoc there. Green tells the Beacon that at the time, "I could see a future where DNA analysis would become a more central part of pathology and a central part of diagnostics." After a stint as an assistant professor, Green worked at the NHGRI for eight years before becoming its third director. "I got on the human genome elevator on day one and have ridden it ever since," Green says adding that "it's treated me very well, and I have a strong interest in seeing this field thrive."

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.