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Hope and Concern

To some people, three-person IVF or mitochondrial replacement is hope for preventing mitochondrial diseases from being passed on to the next generation, while to others, it is the beginning of the development of designer babies, the New York Times Magazine says.

In the US, the Food and Drug Administration regulates this technique, and recently held a hearing to consider allowing clinical trials of mitochondrial replacement.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.