Kathleen Sebelius, the secretary of the US Department of Health and Human Services, has stepped down after a five-year tenure, the New York Times reports. Her resignation comes on the heels of a rocky rollout of the Affordable Care Act that was marred by technical glitches.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.