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He's Making a List, Checking it Twice

Speaking to National Cancer Institute leaders as well as both intramural and extramural investigators last Saturday, Harold Varmus began outlining his "provocative questions exercise," in which he aims to address unanswered questions in cancer research, reports Science Insider. According to Science, Varmus wishes to address "why testicular cancer can be cured with conventional chemotherapy and why obese people are more prone to certain cancers such as colon and breast cancer," and would like to "upend the conventional wisdom that it's impossible to find drugs that block so-called transcription factors, which are proteins that control the expression of genes." Science Insider says that one Varmus' list is complete, the NCI chief may "hold a special competition to invite proposals for several questions and fund, say, 15 of the best ideas."

The Scan

Not Kept "Clean and Sanitary"

A Food and Drug Administration inspection uncovered problems with cross contamination at an Emergent BioSolutions facility, the Wall Street Journal reports.

Resumption Recommendation Expected

The Washington Post reports that US officials are expected to give the go-ahead to resume using Johnson & Johnson's SARS-CoV-2 vaccine.

Canada's New Budget on Science

Science writes that Canada's new budget includes funding for the life sciences, but not as much as hoped for investigator-driven research.

Nature Papers Examine Single-Cell, Multi-Omic SARS-CoV-2 Response; Flatfish Sequences; More

In Nature this week: single-cell, multi-omics analysis provides insight into COVID-19 pathogenesis, evolution of flatfish, and more.